VivoQuantTM: Pre-clinical Image Postprocessing

VivoQuantTM is inviCRO's multi-modality post-processing suite for SPECT, CT, PET, MR, Optical and and Autoradiography imaging data. DICOM, NifTI, and raw data can be imported as well as many proprietary formats from pre-clinical imaging equipment. VivoQuant combines fundamental viewing functionality with powerful tools for fine-tuning images, isolating and analyzing regions of interest, and more. Multiple display modes including orthogonal views, slice views, special co-registration multi-views as well as 3D MIP and volume renderings allow users to optimally view information of interest. Built-in tools allow the imaging scientist to extract the information she or he needs with minimal effort.
Please contact us at for more details on how to trial VivoQuant.

2017-08-22 » VivoQuant 3.5 is Released!

VivoQuant has been cited in over 35 publications so far in 2017! We put together a list of some of the most recent mentions of the software. Thank you to our users who cite the use of VivoQuant and iPACS in their publications. We truly appreciate it. Some highlights include:

Jaiswal S, Hockenbury N, Meyer C, Hoy A, Dardzinski B, Byrnes K. Evaluation of Intranasal Insulin Administration on Regional Metabolic Changes in Rat Brain with Cognitive testing during Uptake using [18F] FDG PET following moderate CCI. Journal of Nuclear Medicine. 2017; 58(1): 655.

James ML, Belichenko NP, Shuhendler AJ, Hoehne A, Andrews LE, Condon C, Nguyen TV, Reiser V, Jones P, Trigg W. [18F] GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer’s Disease. Theranostics. 2017; 7(6): 1422.

Li N, Yu Z, Pham TT, Blower PJ, Yan R. A generic 89Zr labeling method to quantify the in vivo pharmacokinetics of liposomal nanoparticles with positron emission tomography. International journal of nanomedicine. 2017; 12(1): 3281.

VivoQuant and iPACS are critical components of the Invicro Core Lab, supporting CNS and Oncology clinical trials. The integration of data acceptance via our Submission iPACS from over 900 imaging centers worldwide with study management on iPACS and analysis on VivoQuant allows for streamlined workflows on a single platform, end-to-end audit traceability as well as comprehensive quality control.

2016-11-28 » VivoQuant 3.0 Release brings Modeling and Usability Boost

If you were unable to attend the recent VivoQuant 3.0 webinar, a recording is now available here. This webinar highlights the following new features in VivoQuant:

ELECTRONIC CASE REPORT FORM (eCRF) for clinical and general data review applications (in combination with iPACS™)
IMPROVED DATA SELECTION within the Arithmetics, Reorientation, Filtering Operators
IMPROVED 3D ROI TOOL for faster iPACS™ transfers and statistics computations
IMPROVED DATA FORMAT SUPPORT for ECAT7, Dynamic Bruker, MR Solutions, GE Locus image data and others
For a complete list of changes, please visit our change log. On behalf of everyone at inviCRO, we thank you for your continued support and hope you enjoy VivoQuant 3.0. As always, we value your feedback and welcome any questions or comments. If you wish to contact us regarding trial access, please click here.

2015-11-13 » News: Visualize more from your data with VivoQuant 2.5

inviCRO is proud to release the newest version of our image analysis software, VivoQuant 2.5! Presentations and workflow tutorials on new features, as well as other software information, are now available on our updated Youtube channel and blog. This version is made available to our users less than four months after the 2.1 release. New features in 2.5 include:

  • Expanded Tracer Kinetic Modeling package including SRTM, SRTM2, 2TCM, 1TCM, Logan Plot, Logan Reference Plot, and Patlak models
  • Improved Multi-Image Viewer to enhance visualization of multiple datasets and dynamic data
  • New Zoom/Pan Controls to improve navigation speed and performance through your data
  • Re-designed Data List and Color Palettes optimized for user-friendliness
  • New Connect to iPACS workflow making easier to configure your iPACS connection directly from VivoQuant
  • New Multi-Interference Modeling tool for multi-echo GRE MR images to estimate fat fraction
  • Improved VivoScript features and documentation including a new VivoScript debugger for developers
  • Bug fixes, improved data format support, and more!

To upgrade your VivoQuant version, please download from or go to Tools|Update Check within VivoQuant to download the best version for your operating system. inviCRO continues to offer professional services to optimize image analysis, sharing, and storage workflows via specialized software and scripts built upon the VivoQuant and iPACS platforms. Please contact your account representative to learn more and brainstorm ideas for how your workflows might be made more efficient.

2015-07-16 » News: VivoQuant 2.1 has been Released

Less than five months after our release of 2.0, inviCRO would like to introduce version 2.1. The update is a maintenance release of 2.0, providing a number of important bug fixes and a brand new VivoScript toolbar. Version 2.1 also lays the infrastrucure for some major new features coming in our next version -- stay tuned.

Please upgrade your VivoQuant version by going to Tools|Update Check or download directly from the VivoQuant website. Should you have any feedback, please reach out to us either with the built in Service Reporter or by emailing

2015-02-25 » News: VivoQuant 2.0 is Here

inviCRO is pleased to introduce a brand new look and powerful improvements in the latest release: VivoQuant 2.0. Feedback from our outstanding user base and internal development efforts from our image analysis, contract research, and laboratory teams have motivated the features included in the new release. The development team has strived toward building an interface that is at once familiar and considerably more intuitive to enable state-of-the-art image processing, advanced analysis, reporting, and batch processing. New features in 2.0 include:

  • New License Manager for easier licensing support and transfer
  • RGB Support: bring color to your images!
  • Optimized rendering of large 2D data sets (upwards of 100x faster than 1.23)
  • Autoradiography Module: support for raw data formats and quantitative calibration
  • Optimized and More User-friendly Interface
  • Configurable Radiologist/Neurologist Orientation Viewing
  • New data format support: Paravision 6, Trifoil, Gamma Medica PET, and more!
  • MR Bias Field Correction
  • Many more features and bug fixes (Volume Rendering, Fedora OS Support, ...)

To upgrade your VivoQuant version, please go to Tools|Update Check or download directly from the VivoQuant website. inviCRO continues to offer professional services to optimize image analysis, sharing, and storage workflows via specialized software and scripts built upon the VivoQuant and iPACS platforms. Please contact your account representative to learn more and brainstorm ideas for how your workflows might be made more efficient.

2014-04-03 » News: VivoQuant 1.23 released

VivoQuant 1.23: Bridging the gap from image to data

Download your demo version of VivoQuant, today!

inviCRO is proud to announce the latest release of our flagship VivoQuant software. Version 1.23 is the direct result of incorporating your user feature requests with our in-house development efforts.
Our hard-working team is committed to delivering a powerful and intuitive platform for image viewing and analysis. With new and expanded functionality, VivoQuant 1.23 provides the tools to enhance and streamline any demanding workflow for your team.
VivoQuant 1.23 introduces innovative new and improved features, including: To upgrade your VivoQuant version, please go to Tools|Update Check or download directly from the VivoQuant website. inviCRO invites you to attend a live WebEx Demo on April 17th at 11am EST that will highlight the new and improved features of VivoQuant. A workshop style WebEx will be held on April 30th at 11am EST as well. The WebEx meetings will be recorded and posted online for those unable to attend. WebEx details will be sent out the week prior to the Webinar. In addition, inviCRO now offers Profressional Services to support imaging groups. inviCRO will work with your team to create and optimize image data processing and reporting workflows through generation of VivoQuant and iPACS® scripts as well as software customizations. Contact your account representative to learn more about how inviCRO's Profressional Services can improve your workflows. Lastly, Aspect Imaging has partnered with inviCRO to develop and commercialize a software for 3D BLI Reconstruction, LumiQuantTM. LumiQuant is a hardware and software solution from Aspect Imaging to improve spatial localization and quantification of luminescent signal along with providing 3D anatomical co-registration with compact MRI. To learn more Click here. On behalf of the VivoQuant development team and the entirety at inviCRO, we would like to extend our sincere thanks to all of our users for your feedback and support. We hope you enjoy your experience with VivoQuant 1.23 as we look forward to any and all future correspondence. If you have questions or comments, please do not hesitate to contact us. Please visit the inviCRO homepage as well as our LinkedIn page for further details.

2013-02-18 » News: VivoQuant 1.22 released

inviCRO is excited to announce the release of VivoQuant 1.22. With new and expanded functionality, this version continues to deliver the premier multi-modality image viewing and analysis platform which you and your team have come to expect from inviCRO. VivoQuant 1.22 provides enhanced tools to streamline your image analysis workflows for all of your SPECT, CT, PET, MR and optical imaging data.
Please also see attached flyer for more details.

Please join us for an overview of new and improved features in VivoQuant 1.22 (see attached flyer for more details and links):

WebEx Demos on
February 21, 11am EST (US), 5pm CET (Europe)
as well as
March 21, 11am EDT (US), 4pm CET (Europe)

VivoQuant users will be introduced to:

  • Revamped Registration and Reorientation Tool with stronger 2D & 3D capabilities
  • Improved 3D ROI tool with Newly Added Interpolation Tool, Undo/Redo Support and Expanded Keyboard Shortcuts
  • New Dosimetry Tool
  • Expanded VivoScript Capabilities, allowing more batch processing and automation
  • High definition renderings thanks to new Image Magnification Tool
  • VivoQuant Session Tool with iPACS Integrated
  • Improved Data Loading and Handling of DICOM and non-DICOM Image Data
  • Expanded Scriptable Workflows
  • Now also available on Linux (RHEL 5 compatible)
  • and much more!

2013-01-13 » News: Super sized images from VivoQuant

click for full size.
Thanks to the new magnification feature of the upcoming VivoQuant 1.22 you can now blow up your renderings to poster size, e.g. for instance this rendering of a mouse in 3430x8510 pixels (click on image for full size).

2012-10-18 » News: VivoQuant now available on Linux

Linux version of VQ
We are pleased to announce the official availability of VivoQuant 1.22 alpha versions for 64-bit Linux. If you are a Linux user, please provide your feedback to further improve the Linux experience before the final release of VQ 1.22 in December. Currently, we build VQ for RHEL 5 (also compabitle with CentOS 5 and Scientific Linux 5), however, more flavors could be available on request.

VQ 1.22: MPR View meets 3D ROI Tool

A new feature has arrived in VQ 1.22, adding an MPR view to the 3D ROI tool. Thanks to VivoScript, movies such as the above can be rendered completely automatically.

2012-06-06 » News: VivoQuant 1.21 released

inviCRO is excited to announce the release of VivoQuant 1.21. With new and expanded functionality, the development team has been hard at work to continue to deliver an image viewing and analysis platform that is more powerful, flexible, efficient and easier to use for your research needs. VivoQuant users now have access to a new and improved Distance and Annotation Tool, revamped iPACS sync and DICOM proxy clients, new VivoQuant sessions feature, improved data loading and handling of DICOM and non-DICOM image data, expanded scriptable workflows, and much more!

2012-03-07 » News: VivoQuant export renderings to Browser

VivoQuant 1.21 now allows the export of ROI renderings to your favorite (non-IE) web browser. Thanks to the X Toolkit (XTK), sharing your ROI data has become even more simple. Now your audience does not need a VivoQuant license to be able to check out your latest ROIs or Atlas work.
The export is implemented as a VivoScript, using VivoQuant's brand new ScriptEngine, which means the exported web page can be customized very easily.
Currently, experience is best on Chrome and Firefox, however, also in Safari you can enable WebGL. Internet Explorer requires the installation of a plugin.
VivoQuant 1.21 will come with many more VivoScript examples, e.g. automatic segmentation, a humane rat skinner, export of new movie types, etc...