The Quantification Calculator enables a feature unique to the NanoSPECT/CT imaging system: the ability to perform absolute quantification in small-animal SPECT imaging.
The QuantiCalc tool is available going to Advanced Modules > NucMed.
The Quantification Calculator is used to calculate a Quantification Factor. To perform absolute quantification, Quantification Factors must be calculated for each isotope and aperture combination used in the NanoSPECT/CT. The Quantification Factors are stored in the Quantification Database. For information on collecting the data necessary to calculate Quantification Factors, please see the NanoSPECT/CT documentation.
The procedure for collecting Quantification Factor data involves performing a highly-specified SPECT measurement on a syringe filled with isotope. The fields of the QuantiCalc window may then be filled in according to:
|Dose Meter||Record the amount of activity in the syringe in
|NanoSPECT||Record the activity value measured by the NanoSPECT from reconstructed data. Include the time of data collection.|
|Isotope||Select the isotope present in the syringe. Isotopes offered include
|Decay Factor||The information from the Dose Meter, NanoSPECT, and Isotope fields will be used to calculate a decay factor between the time of Dose Meter measurement and data collection.|
|Quantification Factor||The information from the above fields is all combined to determine a Quantification Factor for that particular isotope and aperture. This Quantification Factor can then be entered in the Quantification Database.|
The Quantification Database stores all of the Quantification Factors calculated for any isotope and aperture combination measured with the NanoSPECT/CT.